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=Dimethylsulfoniopropionate-Dependent Demethylase A (DmdA)=

=Dimethylsulfoniopropionate-Dependent Demethylase(DmdA)=

==Introduction==

Dimethylsulfoniopropionate-~~Dependendent~~ Demethylase A (DmdA) is ~~an enzyme produced~~ by ~~marine bacterioplankton in order to demethylate~~ Dimethylsulfoniopropionate (~~DMSP~~).

Dimethylsulfoniproprionate (DMSP) is a common metabolite produced by marine microorganisms and it acts as a significant carbon and sulfur source for marine bacteria. Degradation of DMSP occurs by either the cleavage pathway or the demethylation pathway <ref> Reisch, C.R., Moran, M.A., Whitman, W.B. (2008). Dimethylsulfoniopropionate-Dependent Demethylase (DmdA) from Pelagibacter ubique and Silicibacter pomeroyi. J. Bacteriol. 190: 8018-8024. </ref>. The demethylation pathway is characterized by the conversion of DMSP into methylmercaptopropionate (MMPA). Dimethylsulfoniopropionate-Dependendent Demethylase (DmdA) is the first enzyme in the demethylation pathway and facilitates this conversion by acting as a transferase. While the exact mechanism of DmdA is still unknown, a proposed mechanism has recently been published.

==Structure==

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 <!-- PLEASE ADD YOUR CONTENT BELOW HERE -->
-=Dimethylsulfoniopropionate-Dependent Demethylase A (DmdA)=
+=Dimethylsulfoniopropionate-Dependent Demethylase(DmdA)=
-<Structure load='3TFH' size='500' frame='true' align='right' caption='Dimethylsulfoniopropionate-Dependent Demethylase A (DmdA), [[3TFH]]' scene='Insert optional scene name here' />
+<Structure load='3TFH' size='500' frame='true' align='right' caption='Dimethylsulfoniopropionate-Dependent Demethylase (DmdA), [[3TFH]]' scene='Insert optional scene name here' />
 ==Introduction==
-Dimethylsulfoniopropionate-Dependendent Demethylase A (DmdA) is an enzyme produced by marine bacterioplankton in order to demethylate Dimethylsulfoniopropionate (DMSP).
+Dimethylsulfoniproprionate (DMSP) is a common metabolite produced by marine microorganisms and it acts as a significant carbon and sulfur source for marine bacteria. Degradation of DMSP occurs by either the cleavage pathway or the demethylation pathway <ref> Reisch, C.R., Moran, M.A., Whitman, W.B. (2008). Dimethylsulfoniopropionate-Dependent Demethylase (DmdA) from Pelagibacter ubique and Silicibacter pomeroyi. J. Bacteriol. 190: 8018-8024. </ref>. The demethylation pathway is characterized by the conversion of DMSP into methylmercaptopropionate (MMPA). Dimethylsulfoniopropionate-Dependendent Demethylase (DmdA) is the first enzyme in the demethylation pathway and facilitates this conversion by acting as a transferase. While the exact mechanism of DmdA is still unknown, a proposed mechanism has recently been published.
 ==Structure==