Sandbox Reserved 480: Difference between revisions

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== Phenylalanine Hydroxylase ==

~~[[Image:2pah_bio_r_500.jpg]]~~

Phenylalanine Hydroxylase(<scene name='Sandbox_Reserved_480/Phenylalanine_hydroxylase/1'>PAH</scene>)is a type of enzyme involved in the catalization of phenylalanine into tyrosine.

Phenylalanine Hydroxylase(<scene name='Sandbox_Reserved_480/Phenylalanine_hydroxylase/1'>PAH</scene>)is a type of enzyme involved in the catalization of phenylalanine into tyrosine. It belongs to the family of aromatic amino acid hydroxylases. Some other enzymes in this family include tyrosine hydroxylase and tryptophan hydroxylase. These enzymes require oxygen and forms of pterin to convert their amino acid substrates into products.

~~== Introduction ==~~

== Structure ==

It has been observed as a <scene name='Sandbox_Reserved_480/Dimer/1'>dimer</scene> and tetrameric structure. This is the <scene name='Sandbox_Reserved_480/Active_site/3'>active</scene> site within the subunit. This includes the residues His, His, and

PheOH is a tetrameric enzyme, consisting of 2 asymmetric components. It contains an It has been observed as a <scene name='Sandbox_Reserved_480/Dimer/1'>dimer</scene> and tetrameric structure. This is the <scene name='Sandbox_Reserved_480/Active_site/3'>active</scene> site within the subunit. This includes the residues His, His, and

This enzyme has two <scene name='Sandbox_Reserved_480/Ligands/1'>ligands</scene>, Fe (III) and .

== ~~Medical Implications~~ ==

== Phenylketonuria ==

Phenylalanine hydroxylase is the rate limiting exzyme invovled in the metabolism of phenylalanine. With Fe (III), oxygen, and tetrahydrobiopterin, PheOH hydroxylates Phe into Tyr. Tyr goes on to make L-dopa and eventually dopamine.

== Mechanism ==

== References ==

Sandbox Reserved 480: Difference between revisions

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@@ Line 4: / Line 4: @@
 == Phenylalanine Hydroxylase ==
-[[Image:2pah_bio_r_500.jpg]]
 <Structure load='1tg2' size='400' frame='true' align='right' caption='Phenylalanine Hydroxylase' scene='Phenylalanine Hydroxylase' />
-Phenylalanine Hydroxylase(<scene name='Sandbox_Reserved_480/Phenylalanine_hydroxylase/1'>PAH</scene>)is a type of enzyme involved in the catalization of phenylalanine into tyrosine.
+Phenylalanine Hydroxylase(<scene name='Sandbox_Reserved_480/Phenylalanine_hydroxylase/1'>PAH</scene>)is a type of enzyme involved in the catalization of phenylalanine into tyrosine. It belongs to the family of aromatic amino acid hydroxylases. Some other enzymes in this family include tyrosine hydroxylase and tryptophan hydroxylase. These enzymes require oxygen and forms of pterin to convert their amino acid substrates into products.
-== Introduction ==
 == Structure ==
-It has been observed as a <scene name='Sandbox_Reserved_480/Dimer/1'>dimer</scene> and tetrameric structure. This is the <scene name='Sandbox_Reserved_480/Active_site/3'>active</scene> site within the subunit. This includes the residues His, His, and
+PheOH is a tetrameric enzyme, consisting of 2 asymmetric components. It contains an It has been observed as a <scene name='Sandbox_Reserved_480/Dimer/1'>dimer</scene> and tetrameric structure. This is the <scene name='Sandbox_Reserved_480/Active_site/3'>active</scene> site within the subunit. This includes the residues His, His, and
 This enzyme has two <scene name='Sandbox_Reserved_480/Ligands/1'>ligands</scene>, Fe (III) and .
-== Medical Implications ==
+== Phenylketonuria ==
+Phenylalanine hydroxylase is the rate limiting exzyme invovled in the metabolism of phenylalanine. With Fe (III), oxygen, and tetrahydrobiopterin, PheOH hydroxylates Phe into Tyr. Tyr goes on to make L-dopa and eventually dopamine.
 == Mechanism ==
 == References ==