Sandbox Reserved 473: Difference between revisions
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== Applications == | == Applications == | ||
While kinesins are generally studied for understanding of structure, mechanism and function, kinesin might be implicated in several diseases in which defective transport occurs in cells. Better understanding of the mechanism of kinesin could lead to | While kinesins are generally studied for understanding of structure, mechanism and function, kinesin might be implicated in several diseases in which defective transport occurs in cells. For instance, kinesin may be involved in causing the protein aggregation that leads to neurodegenerative diseases such as Alzheimer's. Better understanding of the mechanism of kinesin, and if and how it is responsible in causing these diseases, could lead to new treatments. Additionally, since kinesin is critically involved in cell replication through mitosis, it could be targeted in cancer treatments as a way to prevent cancer cell division <ref>Mandelkow, E. and Mandelkow, E.M. (2002.) Kinesin motors and disease. Trends in Cell Biol., 12(12): 585-91.</ref>. | ||
== References == | == References == | ||
