Sandbox Reserved 452: Difference between revisions

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== Medical Uses ==

The over expression of c-myc is one of the most common findings in human cancer, however it is still unclear how it acts to promote abnormal cell growth. Studies have shown that the greater amounts of c-myc present the higher your chances are for having cancer. Researchers have been looking into the binding of c-myc with max to see if that would deregulate is expression, taking the c-myc protein out of the organism all together, and mutating certain regions where c-myc binds DNA to try and understand why it effects proliferation eventually causing cancer. One of the most common forms of cancer that c-myc is involved in is [http://en.wikipedia.org/wiki/Burkitt's_lymphoma Burkitts's lymphoma. In this cancer, c-myc proto-oncogene is moved from its normal position on chromosome 8 by recipricol translocation to an enhancer region close to chromosome 14, the gene that is capable of making antibodies. Since antibodies are frequently used in the body to maintain a good immune system, it is frequently transcribed. So c-myc ends up becoming uncontrolably transcribed when it is translocated to this region.

The over expression of c-myc is one of the most common findings in human cancer, however it is still unclear how it acts to promote abnormal cell growth. Studies have shown that the greater amounts of c-myc present the higher your chances are for having cancer. Researchers have been looking into the binding of c-myc with max to see if that would deregulate is expression, taking the c-myc protein out of the organism all together, and mutating certain regions where c-myc binds DNA to try and understand why it effects proliferation eventually causing cancer. One of the most common forms of cancer that c-myc is involved in is [http://en.wikipedia.org/wiki/Burkitt's_lymphoma Burkitts's lymphoma]. In this cancer, c-myc proto-oncogene is moved from its normal position on chromosome 8 by recipricol translocation to an enhancer region close to chromosome 14, the gene that is capable of making antibodies. Since antibodies are frequently used in the body to maintain a good immune system, it is frequently transcribed. So c-myc ends up becoming uncontrolably transcribed when it is translocated to this region.

C-myc could potentially become useful in cancer therapy as a drug, but until more is known about its mechanism and binding, the cure for cancer will still be unknown.

Sandbox Reserved 452: Difference between revisions

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 == Medical Uses  ==
-The over expression of c-myc is one of the most common findings in human cancer, however it is still unclear how it acts to promote abnormal cell growth. Studies have shown that the greater amounts of c-myc present the higher your chances are for having cancer. Researchers have been looking into the binding of c-myc with max to see if that would deregulate is expression, taking the c-myc protein out of the organism all together, and mutating certain regions where c-myc binds DNA to try and understand why it effects proliferation eventually causing cancer. One of the most common forms of cancer that c-myc is involved in is [http://en.wikipedia.org/wiki/Burkitt's_lymphoma Burkitts's lymphoma. In this cancer, c-myc proto-oncogene is moved from its normal position on chromosome 8 by recipricol translocation to an enhancer region close to chromosome 14, the gene that is capable of making antibodies. Since antibodies are frequently used in the body to maintain a good immune system, it is frequently transcribed. So c-myc ends up becoming uncontrolably transcribed when it is translocated to this region.
+The over expression of c-myc is one of the most common findings in human cancer, however it is still unclear how it acts to promote abnormal cell growth. Studies have shown that the greater amounts of c-myc present the higher your chances are for having cancer. Researchers have been looking into the binding of c-myc with max to see if that would deregulate is expression, taking the c-myc protein out of the organism all together, and mutating certain regions where c-myc binds DNA to try and understand why it effects proliferation eventually causing cancer. One of the most common forms of cancer that c-myc is involved in is [http://en.wikipedia.org/wiki/Burkitt's_lymphoma Burkitts's lymphoma]. In this cancer, c-myc proto-oncogene is moved from its normal position on chromosome 8 by recipricol translocation to an enhancer region close to chromosome 14, the gene that is capable of making antibodies. Since antibodies are frequently used in the body to maintain a good immune system, it is frequently transcribed. So c-myc ends up becoming uncontrolably transcribed when it is translocated to this region.
 C-myc could potentially become useful in cancer therapy as a drug, but until more is known about its mechanism and binding, the cure for cancer will still be unknown.