Sandbox Reserved 452: Difference between revisions

Line 2:

== Introduction ==

C-Myc is a [http://en.wikipedia.org/wiki/Transcription_factor transcription factor] involved in the [http://en.wikipedia.org/wiki/Cell_cycle cell cycle] specifically with the stimulation of cell proliferation but is also involved in the regulation of [http://en.wikipedia.org/wiki/Apoptosis apoptosis], [http://en.wikipedia.org/wiki/Cell_differentiation cell differentiation], cell competition, and [http://en.wikipedia.org/wiki/Senescence senescence] <ref>PMID:22510570</ref>. C-Myc is a [http://en.wikipedia.org/wiki/DNA-binding_protein DNA binding protein] and functions primarily by inducing transcription through the formation of [http://en.wikipedia.org/wiki/Protein_dimer heterodimers] primarily with [http://en.wikipedia.org/wiki/MAX_(gene) Max proteins]. C-Myc's interactions are not limited to only Max protiens as it has been shown to interact with [http://en.wikipedia.org/wiki/BRCA1 BRCA1]<ref>PMID:9788437</ref>, [http://en.wikipedia.org/wiki/Mapk1 MAPK1]<ref>PMID: 7957875</ref>, [http://en.wikipedia.org/wiki/P73 p73]<ref>PMID:11844794</ref>, and many more. C-Myc is also a [http://en.wikipedia.org/wiki/Oncogene protooncogene], and when normally expressed is strictly regulated by signals within the cell cycle, so that when a cell is resting its c-myc expression is little while when growing it expresses high levels of c-myc. When normal cells overexpression of c-myc activates a protection pathway and the abnormal cells are thus eliminated from the host organism through apoptosis, thus protecting the organism.

C-Myc is a [http://en.wikipedia.org/wiki/Transcription_factor transcription factor] involved in the [http://en.wikipedia.org/wiki/Cell_cycle cell cycle] specifically with the stimulation of cell proliferation but is also involved in the regulation of [http://en.wikipedia.org/wiki/Apoptosis apoptosis], [http://en.wikipedia.org/wiki/Cell_differentiation cell differentiation], cell competition, and [http://en.wikipedia.org/wiki/Senescence senescence] <ref>PMID:22510570</ref>. C-Myc is a [http://en.wikipedia.org/wiki/DNA-binding_protein DNA binding protein] and functions primarily by inducing transcription through the formation of [http://en.wikipedia.org/wiki/Protein_dimer heterodimers] primarily with [http://en.wikipedia.org/wiki/MAX_(gene) Max proteins]. C-Myc's interactions are not limited to only Max protiens as it has been shown to interact with [http://en.wikipedia.org/wiki/BRCA1 BRCA1]<ref>PMID:9788437</ref>, [http://en.wikipedia.org/wiki/Mapk1 MAPK1]<ref>PMID: 7957875</ref>, [http://en.wikipedia.org/wiki/P73 p73]<ref>PMID:11844794</ref>, and many more. C-Myc is also a [http://en.wikipedia.org/wiki/Oncogene protooncogene], and when normally expressed is strictly regulated by signals within the cell cycle, so that when a cell is resting its c-myc expression is little while when growing it expresses high levels of c-myc. When normal cells have overexpression of c-myc they activates a protection pathway and the abnormal cells are thus eliminated from the host organism through apoptosis, thus protecting the organism.

== Structure ==

Sandbox Reserved 452: Difference between revisions

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 2: / Line 2: @@
 == Introduction ==
-C-Myc is a [http://en.wikipedia.org/wiki/Transcription_factor transcription factor] involved in the [http://en.wikipedia.org/wiki/Cell_cycle cell cycle] specifically with the stimulation of cell proliferation but is also involved in the regulation of [http://en.wikipedia.org/wiki/Apoptosis apoptosis], [http://en.wikipedia.org/wiki/Cell_differentiation cell differentiation], cell competition, and [http://en.wikipedia.org/wiki/Senescence senescence] <ref>PMID:22510570</ref>. C-Myc is a [http://en.wikipedia.org/wiki/DNA-binding_protein DNA binding protein] and functions primarily by inducing transcription through the formation of [http://en.wikipedia.org/wiki/Protein_dimer heterodimers] primarily with [http://en.wikipedia.org/wiki/MAX_(gene) Max proteins]. C-Myc's interactions are not limited to only Max protiens as it has been shown to interact with [http://en.wikipedia.org/wiki/BRCA1 BRCA1]<ref>PMID:9788437</ref>, [http://en.wikipedia.org/wiki/Mapk1 MAPK1]<ref>PMID: 7957875</ref>, [http://en.wikipedia.org/wiki/P73 p73]<ref>PMID:11844794</ref>, and many more. C-Myc is also a [http://en.wikipedia.org/wiki/Oncogene protooncogene], and when normally expressed is strictly regulated by signals within the cell cycle, so that when a cell is resting its c-myc expression is little while when growing it expresses high levels of c-myc. When normal cells overexpression of c-myc activates a protection pathway and the abnormal cells are thus eliminated from the host organism through apoptosis, thus protecting the organism.
+C-Myc is a [http://en.wikipedia.org/wiki/Transcription_factor transcription factor] involved in the [http://en.wikipedia.org/wiki/Cell_cycle cell cycle] specifically with the stimulation of cell proliferation but is also involved in the regulation of [http://en.wikipedia.org/wiki/Apoptosis apoptosis], [http://en.wikipedia.org/wiki/Cell_differentiation cell differentiation], cell competition, and [http://en.wikipedia.org/wiki/Senescence senescence] <ref>PMID:22510570</ref>. C-Myc is a [http://en.wikipedia.org/wiki/DNA-binding_protein DNA binding protein] and functions primarily by inducing transcription through the formation of [http://en.wikipedia.org/wiki/Protein_dimer heterodimers] primarily with [http://en.wikipedia.org/wiki/MAX_(gene) Max proteins]. C-Myc's interactions are not limited to only Max protiens as it has been shown to interact with [http://en.wikipedia.org/wiki/BRCA1 BRCA1]<ref>PMID:9788437</ref>, [http://en.wikipedia.org/wiki/Mapk1 MAPK1]<ref>PMID: 7957875</ref>, [http://en.wikipedia.org/wiki/P73 p73]<ref>PMID:11844794</ref>, and many more. C-Myc is also a [http://en.wikipedia.org/wiki/Oncogene protooncogene], and when normally expressed is strictly regulated by signals within the cell cycle, so that when a cell is resting its c-myc expression is little while when growing it expresses high levels of c-myc. When normal cells have overexpression of c-myc they activates a protection pathway and the abnormal cells are thus eliminated from the host organism through apoptosis, thus protecting the organism.
 == Structure ==