Sandbox Reserved 480: Difference between revisions
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== Phenylketonuria == | == Phenylketonuria == | ||
The image below depicts the possible mutations of the PheOH subunit in each of the three domains. It also gives a representative picture of the tetrameric structure.<ref name="PKU">Nenad Blau, Francjan J van Spronsen, Harvey L Levy. ''Phenylketonuria.'' The Lancet. 376(9750): 1417-1427 (2010)[http://www.sciencedirect.com/science/article/pii/S0140673610609610 DOI: 10.1016/S0140-6736(10)60961-0]</ref> | Mutations of PheOH occur when the gene (PAH) The image below depicts the possible mutations of the PheOH subunit in each of the three domains. It also gives a representative picture of the tetrameric structure.<ref name="PKU">Nenad Blau, Francjan J van Spronsen, Harvey L Levy. ''Phenylketonuria.'' The Lancet. 376(9750): 1417-1427 (2010)[http://www.sciencedirect.com/science/article/pii/S0140673610609610 DOI: 10.1016/S0140-6736(10)60961-0]</ref> | ||
[[Image:Domain phenylketonuria 4.jpg | 500px]] | [[Image:Domain phenylketonuria 4.jpg | 500px]] | ||
== Mechanism == | == Mechanism == | ||
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== References == | == References == | ||
<references /> | <references /> | ||
5. RCSB Protein Data Bank structures used: 2pah, 1tg2, | 5. RCSB Protein Data Bank structures used: 2pah, 1tg2, 1phz, 1kw0, 2phm. http://www.rcsb.org/pdb/results/results.do?outformat=&qrid=E47DFA3E&tabtoshow=Current | ||
