Sandbox Reserved 485: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | <!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | ||
=Ran-GDP= | =Ran-GDP (Ras related nuclear protein)= | ||
<Structure load='3gj0' size='350' frame='true' align='right' caption='(PDB:3GJ0) Crystal Structure of Human RanGDP Asymmetric Unit' scene='Insert optional scene name here' /> | <Structure load='3gj0' size='350' frame='true' align='right' caption='(PDB:3GJ0) Crystal Structure of Human RanGDP Asymmetric Unit' scene='Insert optional scene name here' /> | ||
==Introduction== | ==Introduction== | ||
Ras | Ras related nuclear protein, known as the Ran protein, is the most abundant small GTPase in the cell and serves a variety of key roles in cellular regulation and protein transport. Ran is a binding protein that is a subset of the RAS superfamily that actively binds between GDP and GTP to regulate the import and export of RNA molecules and cytoplasmic material. The Ran protein also plays a key role during interphase and mitosis as the cell progresses through the cell cycle and DNA is synthesized. The majority of the Ran protein is located within the nucleus of eukaryotic cells and interacts with a a variety of proteins due to its diverse uses.<ref>http://www.sciencedirect.com.prox.lib.ncsu.edu/science/article/pii/S0378111911002666</ref> | ||
==Structure== | ==Structure== | ||
