User:Marvin O'Neal/OspC: Difference between revisions
From Proteopedia
Jump to navigationJump to search
| Line 13: | Line 13: | ||
The reported cases of Lyme disease are increasing annually in highly focused geographic locations of the United States. Thus, the abundance of infected ticks with ''B. burgdorferi'' in natural ecosystems is critical for the risk of human Lyme disease. In tick life cycle, the larval ticks are uninfected with ''B. burgdorferi''. However, ''B. burgdorferi'' infection begins while feeding on the blood of natural reservoir hosts such as mice, squirrels, shrews and other small vertebrates. Undergoing successive life stages, the infected nymphal ticks can transmit ''B. burgdorferi'' to incidental vertebrates, including humans. The ecological interaction between the competence of the reservoir hosts and the ticks is the underlying measure of human Lyme disease risk. | The reported cases of Lyme disease are increasing annually in highly focused geographic locations of the United States. Thus, the abundance of infected ticks with ''B. burgdorferi'' in natural ecosystems is critical for the risk of human Lyme disease. In tick life cycle, the larval ticks are uninfected with ''B. burgdorferi''. However, ''B. burgdorferi'' infection begins while feeding on the blood of natural reservoir hosts such as mice, squirrels, shrews and other small vertebrates. Undergoing successive life stages, the infected nymphal ticks can transmit ''B. burgdorferi'' to incidental vertebrates, including humans. The ecological interaction between the competence of the reservoir hosts and the ticks is the underlying measure of human Lyme disease risk. | ||
== Ecological factors responsible for | == Ecological factors responsible for human Lyme disease risk == | ||
* '''Vertebrate Community Composition'''<ref>PMID:15514047</ref>: Two types of environment that the vertebrate hosts reside, which is also called vertebrate host density are interspecific community, which involves organisms of different species and intraspecific community, which is composed of organisms of same species. The hosts living in the community within different species or same species strongly affects the proportion of infected nymphal tick that can cause human Lyme disease. | * '''Vertebrate Community Composition'''<ref>PMID:15514047</ref>: Two types of environment that the vertebrate hosts reside, which is also called vertebrate host density are interspecific community, which involves organisms of different species and intraspecific community, which is composed of organisms of same species. The hosts living in the community within different species or same species strongly affects the proportion of infected nymphal tick that can cause human Lyme disease. | ||
