Sandbox Reserved 498: Difference between revisions
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<Structure load=' | <Structure load='1U9A' size='500' frame='true' align='right' caption='Ubiquitin-conjugating Enzyme, [[Ubc9]]' scene='' /> | ||
[[Image:1U9A.gif|250px|left]] | |||
==Background== | |||
[[Ubc9]], an ubiquitin conjugating enzyme, participates not in the ubiquitinylation pathway but in the sumoylation pathway. This pathway links a SUMO molecule to a targeted protein.(Filip) | |||
Ubc9’s conjugation with [[SUMO]] and not [[ubiquitin]] results in the targeted protein being tagged not for degradation, but to modify the protein for use in regulation, enhancing protein activity, and/or cell cycle functions. (Muller)(Victor) | |||
Ubc9 is one of the 35 known mammalian ubiquitin-conjugating enzymes. These Ubcs bind to ubiquitin or ubiquitin –like proteins.(Sjored) | |||
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