4dwv: Difference between revisions

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[[Image:4dwv.png|left|200px]]
[[Image:4dwv.png|left|200px]]


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{{STRUCTURE_4dwv|  PDB=4dwv  |  SCENE=  }}  
{{STRUCTURE_4dwv|  PDB=4dwv  |  SCENE=  }}  


===Horse alcohol dehydrogenase complexed with NAD+ and 2,3,4,5,6-pentafluorobenzyl alcohol===
===Horse alcohol dehydrogenase complexed with NAD+ and 2,3,4,5,6-pentafluorobenzyl alcohol===


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{{ABSTRACT_PUBMED_22531044}}
{{ABSTRACT_PUBMED_22531044}}


==About this Structure==
==About this Structure==
[[4dwv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DWV OCA].  
[[4dwv]] is a 2 chain structure of [[Alcohol dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DWV OCA].  
 
==See Also==
*[[Alcohol dehydrogenase|Alcohol dehydrogenase]]


==Reference==
==Reference==

Revision as of 04:33, 27 June 2012

File:4dwv.png

Template:STRUCTURE 4dwv

Horse alcohol dehydrogenase complexed with NAD+ and 2,3,4,5,6-pentafluorobenzyl alcohol

Template:ABSTRACT PUBMED 22531044

About this Structure

4dwv is a 2 chain structure of Alcohol dehydrogenase with sequence from Equus caballus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Plapp BV, Ramaswamy S. Atomic-Resolution Structures of Horse Liver Alcohol Dehydrogenase with NAD(+) and Fluoroalcohols Define Strained Michaelis Complexes. Biochemistry. 2012 May 15;51(19):4035-48. Epub 2012 May 1. PMID:22531044 doi:10.1021/bi300378n
  2. Ramaswamy S, Eklund H, Plapp BV. Structures of horse liver alcohol dehydrogenase complexed with NAD+ and substituted benzyl alcohols. Biochemistry. 1994 May 3;33(17):5230-7. PMID:8172897
  3. Rubach JK, Plapp BV. Amino acid residues in the nicotinamide binding site contribute to catalysis by horse liver alcohol dehydrogenase. Biochemistry. 2003 Mar 18;42(10):2907-15. PMID:12627956 doi:10.1021/bi0272656
  4. Venkataramaiah TH, Plapp BV. Formamides mimic aldehydes and inhibit liver alcohol dehydrogenases and ethanol metabolism. J Biol Chem. 2003 Sep 19;278(38):36699-706. Epub 2003 Jul 10. PMID:12855684 doi:10.1074/jbc.M305419200

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