2h4w: Difference between revisions

Revision as of 09:59, 26 July 2012

2h4w is a 3 chain structure of Caspase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Datta D, Scheer JM, Romanowski MJ, Wells JA. An allosteric circuit in caspase-1. J Mol Biol. 2008 Sep 19;381(5):1157-67. Epub 2008 Jun 20. PMID:18590738 doi:10.1016/j.jmb.2008.06.040

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 [[Image:2h4w.png|left|200px]]
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 ===Crystal structure of human caspase-1 (Glu390->Asp) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)===
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