4epr: Difference between revisions

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[[Image:4epr.jpg|left|200px]]
[[Image:4epr.png|left|200px]]


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{{STRUCTURE_4epr|  PDB=4epr  |  SCENE=  }}  
{{STRUCTURE_4epr|  PDB=4epr  |  SCENE=  }}  


===Crystal structure of KRas-GDP (G12D)===
===Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation.===





Revision as of 04:50, 30 May 2012

File:4epr.png

Template:STRUCTURE 4epr

Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation.

Template:ABSTRACT PUBMED 22566140

About this Structure

4epr is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Sun Q, Burke JP, Phan J, Burns MC, Olejniczak ET, Waterson AG, Lee T, Rossanese OW, Fesik SW. Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation. Angew Chem Int Ed Engl. 2012 May 8. doi: 10.1002/anie.201201358. PMID:22566140 doi:10.1002/anie.201201358

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