4atv: Difference between revisions
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{{STRUCTURE_4atv| PDB=4atv | SCENE= }} | |||
===STRUCTURE OF A TRIPLE MUTANT OF THE NHAA DIMER, CRYSTALLISED AT LOW PH=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/NHAA_ECOLI NHAA_ECOLI]] Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Catalyzes the exchange of 2 H(+) per Na(+). Can mediate sodium uptake when a transmembrane pH gradient is applied. Active at alkaline pH. Activity is strongly down-regulated below pH 6.5.<ref>PMID:1645730</ref> | |||
==About this Structure== | |||
[[4atv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ATV OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Escherichia coli]] | |||
[[Category: Cameron, A D.]] | |||
[[Category: Drew, D.]] | |||
[[Category: Iwata, S.]] | |||
[[Category: Lee, C.]] | |||
[[Category: Membrane protein]] | |||
[[Category: Sodium proton antiporter]] | |||
[[Category: Transporter]] | |||
Revision as of 15:49, 10 July 2013
STRUCTURE OF A TRIPLE MUTANT OF THE NHAA DIMER, CRYSTALLISED AT LOW PH
Function
[NHAA_ECOLI] Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Catalyzes the exchange of 2 H(+) per Na(+). Can mediate sodium uptake when a transmembrane pH gradient is applied. Active at alkaline pH. Activity is strongly down-regulated below pH 6.5.[1]
About this Structure
4atv is a 4 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
