1e7w: Difference between revisions

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[[Image:1e7w.png|left|200px]]
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{{STRUCTURE_1e7w|  PDB=1e7w  |  SCENE=  }}  
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===ONE ACTIVE SITE, TWO MODES OF REDUCTION CORRELATE THE MECHANISM OF LEISHMANIA PTERIDINE REDUCTASE WITH PTERIN METABOLISM AND ANTIFOLATE DRUG RESISTANCE IN TRPANOSOMES===
===ONE ACTIVE SITE, TWO MODES OF REDUCTION CORRELATE THE MECHANISM OF LEISHMANIA PTERIDINE REDUCTASE WITH PTERIN METABOLISM AND ANTIFOLATE DRUG RESISTANCE IN TRPANOSOMES===
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{{ABSTRACT_PUBMED_11373620}}
{{ABSTRACT_PUBMED_11373620}}


==About this Structure==
==About this Structure==
[[1e7w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E7W OCA].  
[[1e7w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E7W OCA].  
==See Also==
*[[Pteridine reductase|Pteridine reductase]]


==Reference==
==Reference==
<ref group="xtra">PMID:011373620</ref><ref group="xtra">PMID:012925782</ref><references group="xtra"/>
<ref group="xtra">PMID:011373620</ref><references group="xtra"/><references/>
[[Category: Leishmania major]]
[[Category: Leishmania major]]
[[Category: Pteridine reductase]]
[[Category: Pteridine reductase]]

Revision as of 11:03, 16 April 2014

Template:STRUCTURE 1e7w

ONE ACTIVE SITE, TWO MODES OF REDUCTION CORRELATE THE MECHANISM OF LEISHMANIA PTERIDINE REDUCTASE WITH PTERIN METABOLISM AND ANTIFOLATE DRUG RESISTANCE IN TRPANOSOMES

Template:ABSTRACT PUBMED 11373620

About this Structure

1e7w is a 2 chain structure with sequence from Leishmania major. Full crystallographic information is available from OCA.

See Also

Reference

  1. Gourley DG, Schuttelkopf AW, Leonard GA, Luba J, Hardy LW, Beverley SM, Hunter WN. Pteridine reductase mechanism correlates pterin metabolism with drug resistance in trypanosomatid parasites. Nat Struct Biol. 2001 Jun;8(6):521-5. PMID:11373620 doi:10.1038/88584

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