1y6b: Difference between revisions

Revision as of 13:23, 26 July 2012

1y6b is a 1 chain structure of Vascular Endothelial Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Harris PA, Cheung M, Hunter RN 3rd, Brown ML, Veal JM, Nolte RT, Wang L, Liu W, Crosby RM, Johnson JH, Epperly AH, Kumar R, Luttrell DK, Stafford JA. Discovery and evaluation of 2-anilino-5-aryloxazoles as a novel class of VEGFR2 kinase inhibitors. J Med Chem. 2005 Mar 10;48(5):1610-9. PMID:15743202 doi:10.1021/jm049538w

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 [[Image:1y6b.png|left|200px]]
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 ===Crystal structure of VEGFR2 in complex with a 2-anilino-5-aryl-oxazole inhibitor===
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