1bj0: Difference between revisions
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{{STRUCTURE_1bj0| PDB=1bj0 | SCENE= }} | {{STRUCTURE_1bj0| PDB=1bj0 | SCENE= }} | ||
===TETRACYCLINE CHELATED MG2+-ION INITIATES HELIX UNWINDING FOR TET REPRESSOR INDUCTION=== | ===TETRACYCLINE CHELATED MG2+-ION INITIATES HELIX UNWINDING FOR TET REPRESSOR INDUCTION=== | ||
{{ABSTRACT_PUBMED_9890898}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TETR4_ECOLI TETR4_ECOLI]] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. | |||
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:009890898</ref>< | <ref group="xtra">PMID:009890898</ref><references group="xtra"/><references/> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Hinrichs, W.]] | [[Category: Hinrichs, W.]] | ||
Revision as of 06:44, 10 April 2014
TETRACYCLINE CHELATED MG2+-ION INITIATES HELIX UNWINDING FOR TET REPRESSOR INDUCTION
Template:ABSTRACT PUBMED 9890898
Function
[TETR4_ECOLI] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.
About this Structure
1bj0 is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Orth P, Saenger W, Hinrichs W. Tetracycline-chelated Mg2+ ion initiates helix unwinding in Tet repressor induction. Biochemistry. 1999 Jan 5;38(1):191-8. PMID:9890898 doi:10.1021/bi9816610
