Nitric Oxide Synthase: Difference between revisions

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''Updated June 2012''
''Updated June 2012''


'''Nitric Oxide Synthase''' (NOS) is an enzyme which catalyzes the production of the signaling molecule NO from arginine. In mammals, NOS appears as 3 isozymes: neuronal NOS (nNOS), cytokine-inducible NOS (iNOS) and endothelial NOS (eNOS).  The N-terminal domain of NOS is an oxygenase domain (OD).  NOS cofactors are: NADPH, FAD, FMN, heme and O2. <br />
  In mammals, NOS appears as 3 isozymes: neuronal NOS (nNOS), cytokine-inducible NOS (iNOS) and endothelial NOS (eNOS).  The N-terminal domain of NOS is an oxygenase domain (OD).