4ewa: Difference between revisions
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{{STRUCTURE_4ewa| PDB=4ewa | SCENE= }} | |||
===Study on structure and function relationships in human Pirin with Fe ion=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PIR_HUMAN PIR_HUMAN]] Possible transcriptional coregulator. May contribute to the regulation of cellular processes via its interaction with BCL3. May be required for efficient terminal myeloid maturation of hematopoietic cells. May play a role in the regulation of cell migration. May promote apoptosis when overexpressed. Has quercetin 2,3-dioxygenase activity (in vitro).<ref>PMID:9079676</ref> <ref>PMID:17288615</ref> <ref>PMID:20010624</ref> <ref>PMID:20711196</ref> | |||
==About this Structure== | |||
[[4ewa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EWA OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Quercetin 2,3-dioxygenase]] | |||
[[Category: Chen, L.]] | |||
[[Category: Fu, R.]] | |||
[[Category: Liu, A.]] | |||
[[Category: Liu, F.]] | |||
[[Category: Rehmani, I.]] | |||
[[Category: Serrano, V.]] | |||
[[Category: Wilson, D W.]] | |||
[[Category: Beta sandwich]] | |||
[[Category: Cupin]] | |||
[[Category: Iron]] | |||
[[Category: Metal binding protein]] | |||
[[Category: Nucleus]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Protein binding]] | |||
[[Category: Transcription cofactor activity]] | |||