2ilt: Difference between revisions
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==Overview== | ==Overview== | ||
Potent and selective adamantane sulfone and sulfonamide inhibitors of | Potent and selective adamantane sulfone and sulfonamide inhibitors of 11-beta-HSD-1 have been discovered. Selected compounds from these series have robust pharmacokinetic profiles and strongly inhibit liver, fat, and brain HSD1 for extended periods after oral dosing. | ||
==Disease== | ==Disease== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Judge, R.]] | [[Category: Judge, R.]] | ||
[[Category: Link, J | [[Category: Link, J T.]] | ||
[[Category: Longenecker, K | [[Category: Longenecker, K L.]] | ||
[[Category: Qin, W.]] | [[Category: Qin, W.]] | ||
[[Category: Sorensen, B.]] | [[Category: Sorensen, B.]] | ||
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[[Category: nadp]] | [[Category: nadp]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:53:52 2008'' | ||
