2oxw: Difference between revisions
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[[Category: Luchinat, C.]] | [[Category: Luchinat, C.]] | ||
[[Category: Maletta, M.]] | [[Category: Maletta, M.]] | ||
[[Category: Yeo, K | [[Category: Yeo, K J.]] | ||
[[Category: CA]] | [[Category: CA]] | ||
[[Category: ZN]] | [[Category: ZN]] | ||
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[[Category: mmp-12]] | [[Category: mmp-12]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:23:52 2008'' | ||
Revision as of 16:23, 21 February 2008
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Human MMP-12 complexed with the peptide IAG
Disease
Known diseases associated with this structure: Cardiomyopathy, dilated, 1G OMIM:[188840], Cardiomyopathy, familial hypertrophic OMIM:[188840], Muscular dystrophy, limb-girdle, type 2J OMIM:[188840], Myopathy, early-onset, with fatal cardiomyopathy OMIM:[188840], Myopathy, proximal, with early respiratory muscle involvement OMIM:[188840], Tibial muscular dystrophy, tardive OMIM:[188840]
About this Structure
2OXW is a Single protein structure of sequence from Homo sapiens with ZN and CA as ligands. Active as Macrophage elastase, with EC number 3.4.24.65 Full crystallographic information is available from OCA.
Reference
Snapshots of the reaction mechanism of matrix metalloproteinases., Bertini I, Calderone V, Fragai M, Luchinat C, Maletta M, Yeo KJ, Angew Chem Int Ed Engl. 2006 Dec 4;45(47):7952-5. PMID:17096442
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