3vtm: Difference between revisions
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{{STRUCTURE_3vtm| PDB=3vtm | SCENE= }} | |||
===Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin=== | |||
{{ABSTRACT_PUBMED_21797259}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ISDH_STAAM ISDH_STAAM]] Binds human plasma haptoglobin-hemoglobin complexes, haptoglobin and hemoglobin. Binds haptoglobin-hemoglobin complexes with significantly higher affinity than haptoglobin alone (By similarity). | |||
==About this Structure== | |||
[[3vtm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mu50 Staphylococcus aureus subsp. aureus mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VTM OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:021797259</ref><ref group="xtra">PMID:018667422</ref><references group="xtra"/><references/> | |||
[[Category: Staphylococcus aureus subsp. aureus mu50]] | |||
[[Category: Caaveiro, J M.M.]] | |||
[[Category: Moriwaki, Y.]] | |||
[[Category: Tsumoto, K.]] | |||
[[Category: Vu, N T.]] | |||
[[Category: Cell wall]] | |||
[[Category: Heme binding]] | |||
[[Category: Heme transport]] | |||
[[Category: Heme-binding protein]] | |||
[[Category: Hemin]] | |||
[[Category: Indium]] | |||
[[Category: Metal selectivity]] | |||
[[Category: Metalloporphyrin]] | |||
[[Category: Neat domain]] | |||
[[Category: Ppix]] | |||
Revision as of 07:25, 16 May 2013
Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin
Template:ABSTRACT PUBMED 21797259
Function
[ISDH_STAAM] Binds human plasma haptoglobin-hemoglobin complexes, haptoglobin and hemoglobin. Binds haptoglobin-hemoglobin complexes with significantly higher affinity than haptoglobin alone (By similarity).
About this Structure
3vtm is a 2 chain structure with sequence from Staphylococcus aureus subsp. aureus mu50. Full crystallographic information is available from OCA.
Reference
- Moriwaki Y, Caaveiro JM, Tanaka Y, Tsutsumi H, Hamachi I, Tsumoto K. Molecular basis of recognition of antibacterial porphyrins by heme-transporter IsdH-NEAT3 of Staphylococcus aureus. Biochemistry. 2011 Aug 30;50(34):7311-20. Epub 2011 Aug 4. PMID:21797259 doi:10.1021/bi200493h
- Watanabe M, Tanaka Y, Suenaga A, Kuroda M, Yao M, Watanabe N, Arisaka F, Ohta T, Tanaka I, Tsumoto K. Structural basis for multimeric heme complexation through a specific protein-heme interaction: the case of the third neat domain of IsdH from Staphylococcus aureus. J Biol Chem. 2008 Oct 17;283(42):28649-59. Epub 2008 Jul 30. PMID:18667422 doi:10.1074/jbc.M803383200
