3u7l: Difference between revisions

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~~[[Image:3u7l.jpg|left|200px]]~~

==Crystal structures of the Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors==

~~{{STRUCTURE_3u7l| PDB=3u7l | SCENE= }}~~

== Structural highlights ==

<table><tr><td colspan='2'>[[3u7l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7L OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U7L FirstGlance].

===Crystal structures of the Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors===

</td></tr><tr><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=UDB:(S)-N-(CYCLOPENTYLMETHYL)-2-(3-(3,5-DIFLUOROPHENYL)UREIDO)-N-(2-(HYDROXYAMINO)-2-OXOETHYL)-3,3-DIMETHYLBUTANAMIDE'>UDB</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>

<tr><td class="sblockLbl">[[Non-Standard_Residue|NonStd Res:]]</td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>

<tr><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[3u7k|3u7k]], [[3u7m|3u7m]], [[3u7n|3u7n]]</td></tr>

==~~About this Structure~~==

<tr><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">sacol1100 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>

[[3u7l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7L OCA].

<tr><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </td></tr>

<tr><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u7l RCSB], [http://www.ebi.ac.uk/pdbsum/3u7l PDBsum]</td></tr>

<table>

__TOC__

</StructureSection>

[[Category: Peptide deformylase]]

[[Category: Staphylococcus aureus]]

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-[[Image:3u7l.jpg|left|200px]]
+==Crystal structures of the Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors==
+<StructureSection load='3u7l' size='340' side='right' caption='[[3u7l]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
-{{STRUCTURE_3u7l|  PDB=3u7l  |  SCENE=  }}
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3u7l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U7L FirstGlance]. <br>
-===Crystal structures of the Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors===
+</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UDB:(S)-N-(CYCLOPENTYLMETHYL)-2-(3-(3,5-DIFLUOROPHENYL)UREIDO)-N-(2-(HYDROXYAMINO)-2-OXOETHYL)-3,3-DIMETHYLBUTANAMIDE'>UDB</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
+<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>
+<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3u7k|3u7k]], [[3u7m|3u7m]], [[3u7n|3u7n]]</td></tr>
-==About this Structure==
+<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">sacol1100 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
-[[3u7l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7L OCA].
+<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr>
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u7l RCSB], [http://www.ebi.ac.uk/pdbsum/3u7l PDBsum]</span></td></tr>
+<table>
+__TOC__
+</StructureSection>
 [[Category: Peptide deformylase]]
 [[Category: Staphylococcus aureus]]