3il8: Difference between revisions

Line 4:

==Overview==

The crystal structure of a host defense system chemotactic factor, interleukin 8, has been solved by molecular replacement using as a model, the solution structure derived from nuclear magnetic resonance, experiments. The structure was refined with 2 A x-ray data to an R factor, of 0.187 (0.217 at 1.6 A). A comparison indicates some potential, differences between the structure in solution and in the crystalline, state. Our analysis also predicts that residues 4 through 9 on the amino, terminus and the beta-bend, which includes His-33, may be important for, receptor binding.

The crystal structure of a host defense system chemotactic factor, interleukin 8, has been solved by molecular replacement using as a model the solution structure derived from nuclear magnetic resonance experiments. The structure was refined with 2 A x-ray data to an R factor of 0.187 (0.217 at 1.6 A). A comparison indicates some potential differences between the structure in solution and in the crystalline state. Our analysis also predicts that residues 4 through 9 on the amino terminus and the beta-bend, which includes His-33, may be important for receptor binding.

==Disease==

Line 17:

[[Category: Single protein]]

[[Category: Appella, E.]]

[[Category: Baldwin, E.T.]]

[[Category: Baldwin, E T.]]

[[Category: Charles, R.St.]]

[[Category: Charles, R St.]]

[[Category: Clore, G.M.]]

[[Category: Clore, G M.]]

[[Category: Edwards, B.F.P.]]

[[Category: Edwards, B F.P.]]

[[Category: Gronenborn, A.M.]]

[[Category: Gronenborn, A M.]]

[[Category: Matsushima, K.]]

[[Category: Weber, I.T.]]

[[Category: Weber, I T.]]

[[Category: Wlodawer, A.]]

[[Category: Xuan, J.C.]]

[[Category: Xuan, J C.]]

[[Category: Yamada, M.]]

[[Category: preliminary]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Fri~~ Feb ~~15 17~~:43:36 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:09:55 2008''

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@@ Line 4: / Line 4: @@
 ==Overview==
-The crystal structure of a host defense system chemotactic factor, interleukin 8, has been solved by molecular replacement using as a model, the solution structure derived from nuclear magnetic resonance, experiments. The structure was refined with 2 A x-ray data to an R factor, of 0.187 (0.217 at 1.6 A). A comparison indicates some potential, differences between the structure in solution and in the crystalline, state. Our analysis also predicts that residues 4 through 9 on the amino, terminus and the beta-bend, which includes His-33, may be important for, receptor binding.
+The crystal structure of a host defense system chemotactic factor, interleukin 8, has been solved by molecular replacement using as a model the solution structure derived from nuclear magnetic resonance experiments. The structure was refined with 2 A x-ray data to an R factor of 0.187 (0.217 at 1.6 A). A comparison indicates some potential differences between the structure in solution and in the crystalline state. Our analysis also predicts that residues 4 through 9 on the amino terminus and the beta-bend, which includes His-33, may be important for receptor binding.
 ==Disease==
@@ Line 17: / Line 17: @@
 [[Category: Single protein]]
 [[Category: Appella, E.]]
-[[Category: Baldwin, E.T.]]
+[[Category: Baldwin, E T.]]
-[[Category: Charles, R.St.]]
+[[Category: Charles, R St.]]
-[[Category: Clore, G.M.]]
+[[Category: Clore, G M.]]
-[[Category: Edwards, B.F.P.]]
+[[Category: Edwards, B F.P.]]
-[[Category: Gronenborn, A.M.]]
+[[Category: Gronenborn, A M.]]
 [[Category: Matsushima, K.]]
-[[Category: Weber, I.T.]]
+[[Category: Weber, I T.]]
 [[Category: Wlodawer, A.]]
-[[Category: Xuan, J.C.]]
+[[Category: Xuan, J C.]]
 [[Category: Yamada, M.]]
 [[Category: preliminary]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Feb 15 17:43:36 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:09:55 2008''