P53-DNA Recognition: Difference between revisions
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The <scene name='Sandbox_Reserved_170/Complex/6'>DBD in tetrameric form binds to a response element</scene>, which consists of two half sites. These decameric half sites can be separated by a spacer of flexible length but in this case the spacer is of length zero base pairs. The <scene name='Sandbox_Reserved_170/Complex/7'>p53 tetramer binds DNA as a dimer of dimers</scene> with each dimer binding to one half site of the response element. | The <scene name='Sandbox_Reserved_170/Complex/6'>DBD in tetrameric form binds to a response element</scene>, which consists of two half sites. These decameric half sites can be separated by a spacer of flexible length but in this case the spacer is of length zero base pairs. The <scene name='Sandbox_Reserved_170/Complex/7'>p53 tetramer binds DNA as a dimer of dimers</scene> with each dimer binding to one half site of the response element. | ||
The p53 DBD assumes an <scene name='Sandbox_Reserved_170/Complex/5'> | The p53 DBD assumes an <scene name='Sandbox_Reserved_170/Complex/5'>immunoglobulin fold</scene>, which is a beta sandwich formed by two beta sheet layers, each consisting of antiparallel beta strands. | ||
<scene name='Sandbox_Reserved_170/Complex/8'>Zn ion</scene> | <scene name='Sandbox_Reserved_170/Complex/8'>Zn ion</scene> | ||
