4ft8: Difference between revisions
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{{STRUCTURE_4ft8| PDB=4ft8 | SCENE= }} | |||
===E. coli Catabolite Activator Protein with Cobalt and Sulfate Ligands=== | |||
The | ==Function== | ||
[[http://www.uniprot.org/uniprot/CRP_ECOLI CRP_ECOLI]] This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons. The protein induces a severe bend in the DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP.<ref>PMID:2982847</ref> | |||
==About this Structure== | |||
[[4ft8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FT8 OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Lawson, C L.]] | |||
[[Category: Rao, R.]] | |||
[[Category: Cobalt binding]] | |||
[[Category: Dna binding protein]] | |||
[[Category: Sulfate binding]] | |||
[[Category: Transcription activator]] | |||
[[Category: Winged helix-turn-helix]] | |||
