3ucs: Difference between revisions
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{{STRUCTURE_3ucs| PDB=3ucs | SCENE= }} | |||
===Crystal structure of the complex between CBPA J-domain and CBPM=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CBPA_ECOLI CBPA_ECOLI]] DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM.<ref>PMID:7601860</ref> <ref>PMID:8824642</ref> | |||
==About this Structure== | |||
[[3ucs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12] and [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae_342 Klebsiella pneumoniae 342]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UCS OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Escherichia coli k-12]] | |||
[[Category: Klebsiella pneumoniae 342]] | |||
[[Category: BSGI, Montreal-Kingston Bacterial Structural Genomics Initiative.]] | |||
[[Category: Cygler, M.]] | |||
[[Category: Ekiel, I.]] | |||
[[Category: Sarraf, N S.]] | |||
[[Category: Shi, R.]] | |||
[[Category: Bsgi]] | |||
[[Category: Chaperone]] | |||
[[Category: Co-chaperone regulation]] | |||
[[Category: Montreal-kingston bacterial structural genomics initiative]] | |||
[[Category: Protein-protein complex]] | |||
[[Category: Structural genomic]] | |||
Revision as of 14:11, 3 July 2013
Crystal structure of the complex between CBPA J-domain and CBPM
Function
[CBPA_ECOLI] DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM.[1] [2]
About this Structure
3ucs is a 4 chain structure with sequence from Escherichia coli k-12 and Klebsiella pneumoniae 342. Full crystallographic information is available from OCA.
Reference
- ↑ Ueguchi C, Shiozawa T, Kakeda M, Yamada H, Mizuno T. A study of the double mutation of dnaJ and cbpA, whose gene products function as molecular chaperones in Escherichia coli. J Bacteriol. 1995 Jul;177(13):3894-6. PMID:7601860
- ↑ Wegrzyn A, Taylor K, Wegrzyn G. The cbpA chaperone gene function compensates for dnaJ in lambda plasmid replication during amino acid starvation of Escherichia coli. J Bacteriol. 1996 Oct;178(19):5847-9. PMID:8824642
