12ca: Difference between revisions

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[[Image:12ca.gif|left|200px]]<br /><applet load="12ca" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:12ca.gif|left|200px]]
caption="12ca, resolution 2.4&Aring;" />
 
'''ALTERING THE MOUTH OF A HYDROPHOBIC POCKET. STRUCTURE AND KINETICS OF HUMAN CARBONIC ANHYDRASE II MUTANTS AT RESIDUE VAL-121'''<br />
{{Structure
|PDB= 12ca |SIZE=350|CAPTION= <scene name='initialview01'>12ca</scene>, resolution 2.4&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=HG:MERCURY (II) ION'>HG</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1]
|GENE=
}}
 
'''ALTERING THE MOUTH OF A HYDROPHOBIC POCKET. STRUCTURE AND KINETICS OF HUMAN CARBONIC ANHYDRASE II MUTANTS AT RESIDUE VAL-121'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
12CA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=HG:'>HG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=12CA OCA].  
12CA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=12CA OCA].  


==Reference==
==Reference==
Altering the mouth of a hydrophobic pocket. Structure and kinetics of human carbonic anhydrase II mutants at residue Val-121., Nair SK, Calderone TL, Christianson DW, Fierke CA, J Biol Chem. 1991 Sep 15;266(26):17320-5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=1910042 1910042]
Altering the mouth of a hydrophobic pocket. Structure and kinetics of human carbonic anhydrase II mutants at residue Val-121., Nair SK, Calderone TL, Christianson DW, Fierke CA, J Biol Chem. 1991 Sep 15;266(26):17320-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1910042 1910042]
[[Category: Carbonate dehydratase]]
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: lyase(oxo-acid)]]
[[Category: lyase(oxo-acid)]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:37:57 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:49:07 2008''
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