4b0a: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_4b0a| PDB=4b0a | SCENE= }} | |||
===The high-resolution structure of yTBP-yTAF1 identifies conserved and competing interaction surfaces in transcriptional activation=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TAF1_YEAST TAF1_YEAST]] Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.<ref>PMID:8980232</ref> <ref>PMID:10788514</ref> <ref>PMID:12138208</ref> <ref>PMID:12516863</ref> | |||
==About this Structure== | |||
[[4b0a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B0A OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Histone acetyltransferase]] | |||
[[Category: Saccharomyces cerevisiae]] | |||
[[Category: Anandapadamanaban, M.]] | |||
[[Category: Andresen, C.]] | |||
[[Category: Ikura, M.]] | |||
[[Category: Kokubo, T.]] | |||
[[Category: Moche, M.]] | |||
[[Category: Siponen, M.]] | |||
[[Category: Sunnerhagen, M.]] | |||
[[Category: Transcription]] | |||