1a3w: Difference between revisions

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[[Image:1a3w.gif|left|200px]]<br /><applet load="1a3w" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1a3w.gif|left|200px]]
caption="1a3w, resolution 3.0&Aring;" />
 
'''PYRUVATE KINASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH FBP, PG, MN2+ AND K+'''<br />
{{Structure
|PDB= 1a3w |SIZE=350|CAPTION= <scene name='initialview01'>1a3w</scene>, resolution 3.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PGA:2-PHOSPHOGLYCOLIC+ACID'>PGA</scene>, <scene name='pdbligand=FBP:FRUCTOSE-1,6-DIPHOSPHATE'>FBP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> and <scene name='pdbligand=K:POTASSIUM ION'>K</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40]
|GENE=
}}
 
'''PYRUVATE KINASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH FBP, PG, MN2+ AND K+'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1A3W is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=PGA:'>PGA</scene>, <scene name='pdbligand=FBP:'>FBP</scene>, <scene name='pdbligand=MN:'>MN</scene> and <scene name='pdbligand=K:'>K</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. The following page contains interesting information on the relation of 1A3W with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb50_1.html The Glycolytic Enzymes]]. Active as [http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A3W OCA].  
1A3W is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. The following page contains interesting information on the relation of 1A3W with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb50_1.html The Glycolytic Enzymes]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A3W OCA].  


==Reference==
==Reference==
The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate., Jurica MS, Mesecar A, Heath PJ, Shi W, Nowak T, Stoddard BL, Structure. 1998 Feb 15;6(2):195-210. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9519410 9519410]
The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate., Jurica MS, Mesecar A, Heath PJ, Shi W, Nowak T, Stoddard BL, Structure. 1998 Feb 15;6(2):195-210. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9519410 9519410]
[[Category: Pyruvate kinase]]
[[Category: Pyruvate kinase]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: tranferase]]
[[Category: tranferase]]


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