1a4m: Difference between revisions

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[[Image:1a4m.gif|left|200px]]<br /><applet load="1a4m" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1a4m.gif|left|200px]]
caption="1a4m, resolution 1.95&Aring;" />
 
'''ADA STRUCTURE COMPLEXED WITH PURINE RIBOSIDE AT PH 7.0'''<br />
{{Structure
|PDB= 1a4m |SIZE=350|CAPTION= <scene name='initialview01'>1a4m</scene>, resolution 1.95&Aring;
|SITE= <scene name='pdbsite=CIA:The+Site+Binds+A+And+Convert+It+To+I+And+Ammoniagene'>CIA</scene>, <scene name='pdbsite=CIB:The+Site+Binds+A+And+Convert+It+To+I+And+Ammoniagene'>CIB</scene>, <scene name='pdbsite=CIC:The+Site+Binds+A+And+Convert+It+To+I+And+Ammoniagene'>CIC</scene> and <scene name='pdbsite=CID:The+Site+Binds+A+And+Convert+It+To+I+And+Ammoniagene'>CID</scene>
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=PRH:6-HYDROXY-1,6-DIHYDRO PURINE NUCLEOSIDE'>PRH</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Adenosine_deaminase Adenosine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.4 3.5.4.4]
|GENE=
}}
 
'''ADA STRUCTURE COMPLEXED WITH PURINE RIBOSIDE AT PH 7.0'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1A4M is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=PRH:'>PRH</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Adenosine_deaminase Adenosine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.4 3.5.4.4] Known structural/functional Sites: <scene name='pdbsite=CIA:The+Site+Binds+A+And+Convert+It+To+I+And+Ammoniagene'>CIA</scene>, <scene name='pdbsite=CIB:The+Site+Binds+A+And+Convert+It+To+I+And+Ammoniagene'>CIB</scene>, <scene name='pdbsite=CIC:The+Site+Binds+A+And+Convert+It+To+I+And+Ammoniagene'>CIC</scene> and <scene name='pdbsite=CID:The+Site+Binds+A+And+Convert+It+To+I+And+Ammoniagene'>CID</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4M OCA].  
1A4M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A4M OCA].  


==Reference==
==Reference==
Complexes of adenosine deaminase with two potent inhibitors: X-ray structures in four independent molecules at pH of maximum activity., Wang Z, Quiocho FA, Biochemistry. 1998 Jun 9;37(23):8314-24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9622483 9622483]
Complexes of adenosine deaminase with two potent inhibitors: X-ray structures in four independent molecules at pH of maximum activity., Wang Z, Quiocho FA, Biochemistry. 1998 Jun 9;37(23):8314-24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9622483 9622483]
[[Category: Adenosine deaminase]]
[[Category: Adenosine deaminase]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: purine riboside]]
[[Category: purine riboside]]


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