1a5o: Difference between revisions

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[[Image:1a5o.gif|left|200px]]<br /><applet load="1a5o" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1a5o.gif|left|200px]]
caption="1a5o, resolution 2.5&Aring;" />
 
'''K217C VARIANT OF KLEBSIELLA AEROGENES UREASE, CHEMICALLY RESCUED BY FORMATE AND NICKEL'''<br />
{{Structure
|PDB= 1a5o |SIZE=350|CAPTION= <scene name='initialview01'>1a5o</scene>, resolution 2.5&Aring;
|SITE= <scene name='pdbsite=ACT:Residue+Implicated+In+Catalysis'>ACT</scene> and <scene name='pdbsite=NIL:Ni+Metallocenter'>NIL</scene>
|LIGAND= <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene> and <scene name='pdbligand=FMT:FORMIC ACID'>FMT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Urease Urease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.5 3.5.1.5]
|GENE= UREA, UREB, UREC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28451 Klebsiella aerogenes])
}}
 
'''K217C VARIANT OF KLEBSIELLA AEROGENES UREASE, CHEMICALLY RESCUED BY FORMATE AND NICKEL'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1A5O is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Klebsiella_aerogenes Klebsiella aerogenes] with <scene name='pdbligand=NI:'>NI</scene> and <scene name='pdbligand=FMT:'>FMT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Urease Urease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.5 3.5.1.5] Known structural/functional Sites: <scene name='pdbsite=ACT:Residue+Implicated+In+Catalysis'>ACT</scene> and <scene name='pdbsite=NIL:Ni+Metallocenter'>NIL</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A5O OCA].  
1A5O is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Klebsiella_aerogenes Klebsiella aerogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A5O OCA].  


==Reference==
==Reference==
Chemical rescue of Klebsiella aerogenes urease variants lacking the carbamylated-lysine nickel ligand., Pearson MA, Schaller RA, Michel LO, Karplus PA, Hausinger RP, Biochemistry. 1998 Apr 28;37(17):6214-20. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9558361 9558361]
Chemical rescue of Klebsiella aerogenes urease variants lacking the carbamylated-lysine nickel ligand., Pearson MA, Schaller RA, Michel LO, Karplus PA, Hausinger RP, Biochemistry. 1998 Apr 28;37(17):6214-20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9558361 9558361]
[[Category: Klebsiella aerogenes]]
[[Category: Klebsiella aerogenes]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: nickel metalloenzyme]]
[[Category: nickel metalloenzyme]]


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