1a71: Difference between revisions

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[[Image:1a71.gif|left|200px]]<br /><applet load="1a71" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1a71.gif|left|200px]]
caption="1a71, resolution 2.0&Aring;" />
 
'''TERNARY COMPLEX OF AN ACTIVE SITE DOUBLE MUTANT OF HORSE LIVER ALCOHOL DEHYDROGENASE, PHE93=>TRP, VAL203=>ALA WITH NAD AND TRIFLUOROETHANOL'''<br />
{{Structure
|PDB= 1a71 |SIZE=350|CAPTION= <scene name='initialview01'>1a71</scene>, resolution 2.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene> and <scene name='pdbligand=ETF:TRIFLUOROETHANOL'>ETF</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1]
|GENE= LADH F93W V203A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9796 Equus caballus])
}}
 
'''TERNARY COMPLEX OF AN ACTIVE SITE DOUBLE MUTANT OF HORSE LIVER ALCOHOL DEHYDROGENASE, PHE93=>TRP, VAL203=>ALA WITH NAD AND TRIFLUOROETHANOL'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1A71 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=NAD:'>NAD</scene> and <scene name='pdbligand=ETF:'>ETF</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A71 OCA].  
1A71 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A71 OCA].  


==Reference==
==Reference==
Active site modifications in a double mutant of liver alcohol dehydrogenase: structural studies of two enzyme-ligand complexes., Colby TD, Bahnson BJ, Chin JK, Klinman JP, Goldstein BM, Biochemistry. 1998 Jun 30;37(26):9295-304. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9649310 9649310]
Active site modifications in a double mutant of liver alcohol dehydrogenase: structural studies of two enzyme-ligand complexes., Colby TD, Bahnson BJ, Chin JK, Klinman JP, Goldstein BM, Biochemistry. 1998 Jun 30;37(26):9295-304. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9649310 9649310]
[[Category: Alcohol dehydrogenase]]
[[Category: Alcohol dehydrogenase]]
[[Category: Equus caballus]]
[[Category: Equus caballus]]
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[[Category: oxidoreductase (nad(a)-choh(d))]]
[[Category: oxidoreductase (nad(a)-choh(d))]]


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