1a7t: Difference between revisions

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[[Image:1a7t.gif|left|200px]]<br /><applet load="1a7t" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1a7t.gif|left|200px]]
caption="1a7t, resolution 1.85&Aring;" />
 
'''METALLO-BETA-LACTAMASE WITH MES'''<br />
{{Structure
|PDB= 1a7t |SIZE=350|CAPTION= <scene name='initialview01'>1a7t</scene>, resolution 1.85&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> and <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC ACID'>MES</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6]
|GENE= CCRA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=817 Bacteroides fragilis])
}}
 
'''METALLO-BETA-LACTAMASE WITH MES'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1A7T is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacteroides_fragilis Bacteroides fragilis] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=MES:'>MES</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A7T OCA].  
1A7T is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacteroides_fragilis Bacteroides fragilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A7T OCA].  


==Reference==
==Reference==
Unanticipated inhibition of the metallo-beta-lactamase from Bacteroides fragilis by 4-morpholineethanesulfonic acid (MES): a crystallographic study at 1.85-A resolution., Fitzgerald PM, Wu JK, Toney JH, Biochemistry. 1998 May 12;37(19):6791-800. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9578564 9578564]
Unanticipated inhibition of the metallo-beta-lactamase from Bacteroides fragilis by 4-morpholineethanesulfonic acid (MES): a crystallographic study at 1.85-A resolution., Fitzgerald PM, Wu JK, Toney JH, Biochemistry. 1998 May 12;37(19):6791-800. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9578564 9578564]
[[Category: Bacteroides fragilis]]
[[Category: Bacteroides fragilis]]
[[Category: Beta-lactamase]]
[[Category: Beta-lactamase]]
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[[Category: zinc]]
[[Category: zinc]]


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