1a8r: Difference between revisions

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[[Image:1a8r.gif|left|200px]]<br /><applet load="1a8r" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1a8r.gif|left|200px]]
caption="1a8r, resolution 2.1&Aring;" />
 
'''GTP CYCLOHYDROLASE I (H112S MUTANT) IN COMPLEX WITH GTP'''<br />
{{Structure
|PDB= 1a8r |SIZE=350|CAPTION= <scene name='initialview01'>1a8r</scene>, resolution 2.1&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=GTP:GUANOSINE-5'-TRIPHOSPHATE'>GTP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/GTP_cyclohydrolase_I GTP cyclohydrolase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.16 3.5.4.16]
|GENE=
}}
 
'''GTP CYCLOHYDROLASE I (H112S MUTANT) IN COMPLEX WITH GTP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1A8R is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=GTP:'>GTP</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/GTP_cyclohydrolase_I GTP cyclohydrolase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.16 3.5.4.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A8R OCA].  
1A8R is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A8R OCA].  


==Reference==
==Reference==
Biosynthesis of pteridines. Reaction mechanism of GTP cyclohydrolase I., Rebelo J, Auerbach G, Bader G, Bracher A, Nar H, Hosl C, Schramek N, Kaiser J, Bacher A, Huber R, Fischer M, J Mol Biol. 2003 Feb 14;326(2):503-16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12559918 12559918]
Biosynthesis of pteridines. Reaction mechanism of GTP cyclohydrolase I., Rebelo J, Auerbach G, Bader G, Bracher A, Nar H, Hosl C, Schramek N, Kaiser J, Bacher A, Huber R, Fischer M, J Mol Biol. 2003 Feb 14;326(2):503-16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12559918 12559918]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: GTP cyclohydrolase I]]
[[Category: GTP cyclohydrolase I]]
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[[Category: purine hydrolysis]]
[[Category: purine hydrolysis]]


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