1aaq: Difference between revisions
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[[Image:1aaq.jpg|left|200px]] | [[Image:1aaq.jpg|left|200px]] | ||
'''HYDROXYETHYLENE ISOSTERE INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS-1 PROTEASE: STRUCTURE-ACTIVITY ANALYSIS USING ENZYME KINETICS, X-RAY CRYSTALLOGRAPHY, AND INFECTED T-CELL ASSAYS''' | {{Structure | ||
|PDB= 1aaq |SIZE=350|CAPTION= <scene name='initialview01'>1aaq</scene>, resolution 2.5Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=PSI:2-(2-{5-[2-(2-AMINO-PROPIONYLAMINO)-PROPIONYLAMINO]-4-HYDROXY-6-PHENYL-HEXANOYLAMINO}-3-METHYL-BUTYRYLAMINO)-3-METHYL-BUTYRIC ACID METHYL ESTER'>PSI</scene> | |||
|ACTIVITY= | |||
|GENE= | |||
}} | |||
'''HYDROXYETHYLENE ISOSTERE INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS-1 PROTEASE: STRUCTURE-ACTIVITY ANALYSIS USING ENZYME KINETICS, X-RAY CRYSTALLOGRAPHY, AND INFECTED T-CELL ASSAYS''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1AAQ is a [ | 1AAQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AAQ OCA]. | ||
==Reference== | ==Reference== | ||
Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, X-ray crystallography, and infected T-cell assays., Dreyer GB, Lambert DM, Meek TD, Carr TJ, Tomaszek TA Jr, Fernandez AV, Bartus H, Cacciavillani E, Hassell AM, Minnich M, et al., Biochemistry. 1992 Jul 28;31(29):6646-59. PMID:[http:// | Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, X-ray crystallography, and infected T-cell assays., Dreyer GB, Lambert DM, Meek TD, Carr TJ, Tomaszek TA Jr, Fernandez AV, Bartus H, Cacciavillani E, Hassell AM, Minnich M, et al., Biochemistry. 1992 Jul 28;31(29):6646-59. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1637805 1637805] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: hydrolase(acid protease)]] | [[Category: hydrolase(acid protease)]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:55:12 2008'' | ||
