1aaw: Difference between revisions

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[[Image:1aaw.jpg|left|200px]]~~<br /><applet load~~="1aaw~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:1aaw.jpg|left|200px]]

~~caption="~~1aaw, resolution 2.4Å" />

'''THE STRUCTURAL BASIS FOR THE ALTERED SUBSTRATE SPECIFICITY OF THE R292D ACTIVE SITE MUTANT OF ASPARTATE AMINOTRANSFERASE FROM E. COLI'''~~<br />~~

{{Structure

|PDB= 1aaw |SIZE=350|CAPTION= <scene name='initialview01'>1aaw</scene>, resolution 2.4Å

|SITE=

|LIGAND= <scene name='pdbligand=PLP:PYRIDOXAL-5'-PHOSPHATE'>PLP</scene>

|ACTIVITY= [http://en.wikipedia.org/wiki/Aspartate_transaminase Aspartate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.1 2.6.1.1]

|GENE=

}}

'''THE STRUCTURAL BASIS FOR THE ALTERED SUBSTRATE SPECIFICITY OF THE R292D ACTIVE SITE MUTANT OF ASPARTATE AMINOTRANSFERASE FROM E. COLI'''

==Overview==

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==About this Structure==

1AAW is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] ~~with <scene name='pdbligand=PLP:'>PLP</scene> as [http://en.wikipedia~~.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Aspartate_transaminase Aspartate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.1 2.6.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AAW OCA].

1AAW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AAW OCA].

==Reference==

The structural basis for the altered substrate specificity of the R292D active site mutant of aspartate aminotransferase from E. coli., Almo SC, Smith DL, Danishefsky AT, Ringe D, Protein Eng. 1994 Mar;7(3):405-12. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~7909946 7909946]

The structural basis for the altered substrate specificity of the R292D active site mutant of aspartate aminotransferase from E. coli., Almo SC, Smith DL, Danishefsky AT, Ringe D, Protein Eng. 1994 Mar;7(3):405-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7909946 7909946]

[[Category: Aspartate transaminase]]

[[Category: Escherichia coli]]

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[[Category: aminotransferase]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21 11~~:42:41 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:55:19 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1aaw.jpg|left|200px]]<br /><applet load="1aaw" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1aaw.jpg|left|200px]]
-caption="1aaw, resolution 2.4&Aring;" />
-'''THE STRUCTURAL BASIS FOR THE ALTERED SUBSTRATE SPECIFICITY OF THE R292D ACTIVE SITE MUTANT OF ASPARTATE AMINOTRANSFERASE FROM E. COLI'''<br />
+ {{Structure
+|PDB= 1aaw |SIZE=350|CAPTION= <scene name='initialview01'>1aaw</scene>, resolution 2.4&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=PLP:PYRIDOXAL-5'-PHOSPHATE'>PLP</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Aspartate_transaminase Aspartate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.1 2.6.1.1]
+|GENE=
+}}
+'''THE STRUCTURAL BASIS FOR THE ALTERED SUBSTRATE SPECIFICITY OF THE R292D ACTIVE SITE MUTANT OF ASPARTATE AMINOTRANSFERASE FROM E. COLI'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-AAW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=PLP:'>PLP</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Aspartate_transaminase Aspartate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.1 2.6.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AAW OCA].
+AAW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AAW OCA].
 ==Reference==
-The structural basis for the altered substrate specificity of the R292D active site mutant of aspartate aminotransferase from E. coli., Almo SC, Smith DL, Danishefsky AT, Ringe D, Protein Eng. 1994 Mar;7(3):405-12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7909946 7909946]
+The structural basis for the altered substrate specificity of the R292D active site mutant of aspartate aminotransferase from E. coli., Almo SC, Smith DL, Danishefsky AT, Ringe D, Protein Eng. 1994 Mar;7(3):405-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7909946 7909946]
 [[Category: Aspartate transaminase]]
 [[Category: Escherichia coli]]
@@ Line 21: / Line 30: @@
 [[Category: aminotransferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:42:41 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:55:19 2008''