1aft: Difference between revisions
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[[Image:1aft.gif|left|200px]]< | [[Image:1aft.gif|left|200px]] | ||
'''SMALL SUBUNIT C-TERMINAL INHIBITORY PEPTIDE OF MOUSE RIBONUCLEOTIDE REDUCTASE AS BOUND TO THE LARGE SUBUNIT, NMR, 26 STRUCTURES''' | {{Structure | ||
|PDB= 1aft |SIZE=350|CAPTION= <scene name='initialview01'>1aft</scene> | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=ACE:ACETYL GROUP'>ACE</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] | |||
|GENE= | |||
}} | |||
'''SMALL SUBUNIT C-TERMINAL INHIBITORY PEPTIDE OF MOUSE RIBONUCLEOTIDE REDUCTASE AS BOUND TO THE LARGE SUBUNIT, NMR, 26 STRUCTURES''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1AFT is a [ | 1AFT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AFT OCA]. | ||
==Reference== | ==Reference== | ||
NMR structure of an inhibitory R2 C-terminal peptide bound to mouse ribonucleotide reductase R1 subunit., Fisher A, Laub PB, Cooperman BS, Nat Struct Biol. 1995 Nov;2(11):951-5. PMID:[http:// | NMR structure of an inhibitory R2 C-terminal peptide bound to mouse ribonucleotide reductase R1 subunit., Fisher A, Laub PB, Cooperman BS, Nat Struct Biol. 1995 Nov;2(11):951-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7583667 7583667] | ||
[[Category: Ribonucleoside-diphosphate reductase]] | [[Category: Ribonucleoside-diphosphate reductase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: ACE]] | [[Category: ACE]] | ||
[[Category: nonstandard type i turn]] | [[Category: nonstandard type i turn]] | ||
[[Category: peptide | [[Category: peptide inhibitor]] | ||
[[Category: restrained molecular | [[Category: restrained molecular dynamic]] | ||
[[Category: ribonucleotide reductase]] | [[Category: ribonucleotide reductase]] | ||
[[Category: transferred noesy]] | [[Category: transferred noesy]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:56:56 2008'' | ||
Revision as of 07:56, 20 March 2008
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| 1aft | |||||||||||||
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| Ligands: | ACE | ||||||||||||
| Activity: | Ribonucleoside-diphosphate reductase, with EC number 1.17.4.1 | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
SMALL SUBUNIT C-TERMINAL INHIBITORY PEPTIDE OF MOUSE RIBONUCLEOTIDE REDUCTASE AS BOUND TO THE LARGE SUBUNIT, NMR, 26 STRUCTURES
Overview
The structure of peptide N-AcYTLDADF when bound to the large subunit of mouse ribonucleotide reductase has been elucidated by transfer NOE. This structure suggests a general design for type 1 RR inhibitors.
About this Structure
1AFT is a Single protein structure of sequence from [1]. Full crystallographic information is available from OCA.
Reference
NMR structure of an inhibitory R2 C-terminal peptide bound to mouse ribonucleotide reductase R1 subunit., Fisher A, Laub PB, Cooperman BS, Nat Struct Biol. 1995 Nov;2(11):951-5. PMID:7583667
Page seeded by OCA on Thu Mar 20 09:56:56 2008
