1ah4: Difference between revisions

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[[Image:1ah4.gif|left|200px]]<br /><applet load="1ah4" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ah4.gif|left|200px]]
caption="1ah4, resolution 2.0&Aring;" />
 
'''PIG ALDOSE REDUCTASE, HOLO FORM'''<br />
{{Structure
|PDB= 1ah4 |SIZE=350|CAPTION= <scene name='initialview01'>1ah4</scene>, resolution 2.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE'>NAP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21]
|GENE=
}}
 
'''PIG ALDOSE REDUCTASE, HOLO FORM'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1AH4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa] with <scene name='pdbligand=NAP:'>NAP</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AH4 OCA].  
1AH4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AH4 OCA].  


==Reference==
==Reference==
A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil., Urzhumtsev A, Tete-Favier F, Mitschler A, Barbanton J, Barth P, Urzhumtseva L, Biellmann JF, Podjarny A, Moras D, Structure. 1997 May 15;5(5):601-12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9195881 9195881]
A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil., Urzhumtsev A, Tete-Favier F, Mitschler A, Barbanton J, Barth P, Urzhumtseva L, Biellmann JF, Podjarny A, Moras D, Structure. 1997 May 15;5(5):601-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9195881 9195881]
[[Category: Aldehyde reductase]]
[[Category: Aldehyde reductase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: oxidoreductase]]
[[Category: oxidoreductase]]


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