1aiq: Difference between revisions

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[[Image:1aiq.jpg|left|200px]]<br /><applet load="1aiq" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1aiq.jpg|left|200px]]
caption="1aiq, resolution 2.2&Aring;" />
 
'''CRYSTAL STRUCTURE OF THYMIDYLATE SYNTHASE R126E MUTANT'''<br />
{{Structure
|PDB= 1aiq |SIZE=350|CAPTION= <scene name='initialview01'>1aiq</scene>, resolution 2.2&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=UMP:2'-DEOXYURIDINE+5'-MONOPHOSPHATE'>UMP</scene> and <scene name='pdbligand=CB3:10-PROPARGYL-5,8-DIDEAZAFOLIC ACID'>CB3</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45]
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF THYMIDYLATE SYNTHASE R126E MUTANT'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1AIQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=UMP:'>UMP</scene> and <scene name='pdbligand=CB3:'>CB3</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AIQ OCA].  
1AIQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AIQ OCA].  


==Reference==
==Reference==
Crystal structures of a marginally active thymidylate synthase mutant, Arg 126--&gt;Glu., Strop P, Changchien L, Maley F, Montfort WR, Protein Sci. 1997 Dec;6(12):2504-11. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9416600 9416600]
Crystal structures of a marginally active thymidylate synthase mutant, Arg 126--&gt;Glu., Strop P, Changchien L, Maley F, Montfort WR, Protein Sci. 1997 Dec;6(12):2504-11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9416600 9416600]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transferase]]
[[Category: transferase]]


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