1ap4: Difference between revisions

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[[Image:1ap4.gif|left|200px]]<br /><applet load="1ap4" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ap4.gif|left|200px]]
caption="1ap4" />
 
'''REGULATORY DOMAIN OF HUMAN CARDIAC TROPONIN C IN THE CALCIUM-SATURATED STATE, NMR, 40 STRUCTURES'''<br />
{{Structure
|PDB= 1ap4 |SIZE=350|CAPTION= <scene name='initialview01'>1ap4</scene>
|SITE= <scene name='pdbsite=CUM:Ca+Binding+Site+II'>CUM</scene>
|LIGAND= <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
|ACTIVITY=  
|GENE=  
}}
 
'''REGULATORY DOMAIN OF HUMAN CARDIAC TROPONIN C IN THE CALCIUM-SATURATED STATE, NMR, 40 STRUCTURES'''
 


==Overview==
==Overview==
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==Disease==
==Disease==
Known diseases associated with this structure: Cardiomyopathy, familial hypertrophic, 192600 (3) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191040 191040]]
Known diseases associated with this structure: Cardiomyopathy, dilated, 1Z OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191040 191040]], Cardiomyopathy, familial hypertrophic, 192600 (3) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191040 191040]]


==About this Structure==
==About this Structure==
1AP4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=CUM:Ca+Binding+Site+II'>CUM</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AP4 OCA].  
1AP4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AP4 OCA].  


==Reference==
==Reference==
Calcium-induced structural transition in the regulatory domain of human cardiac troponin C., Spyracopoulos L, Li MX, Sia SK, Gagne SM, Chandra M, Solaro RJ, Sykes BD, Biochemistry. 1997 Oct 7;36(40):12138-46. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9315850 9315850]
Calcium-induced structural transition in the regulatory domain of human cardiac troponin C., Spyracopoulos L, Li MX, Sia SK, Gagne SM, Chandra M, Solaro RJ, Sykes BD, Biochemistry. 1997 Oct 7;36(40):12138-46. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9315850 9315850]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: troponin c]]
[[Category: troponin c]]


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