1s63: Difference between revisions

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Revision as of 13:06, 25 July 2012

File:1s63.png

Template:STRUCTURE 1s63

Human protein farnesyltransferase complexed with L-778,123 and FPP

Template:ABSTRACT PUBMED 15248757

About this Structure

1s63 is a 2 chain structure of Farnesyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Reid TS, Long SB, Beese LS. Crystallographic analysis reveals that anticancer clinical candidate L-778,123 inhibits protein farnesyltransferase and geranylgeranyltransferase-I by different binding modes. Biochemistry. 2004 Jul 20;43(28):9000-8. PMID:15248757 doi:10.1021/bi049280b

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