1bb0: Difference between revisions

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[[Image:1bb0.jpg|left|200px]]<br /><applet load="1bb0" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1bb0.jpg|left|200px]]
caption="1bb0, resolution 2.1&Aring;" />
 
'''THROMBIN INHIBITORS WITH RIGID TRIPEPTIDYL ALDEHYDES'''<br />
{{Structure
|PDB= 1bb0 |SIZE=350|CAPTION= <scene name='initialview01'>1bb0</scene>, resolution 2.1&Aring;
|SITE= <scene name='pdbsite=CAT:Active+Site'>CAT</scene>
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PMS:BENZYLSULFINIC+ACID'>PMS</scene> and <scene name='pdbligand=NVA:NORVALINE'>NVA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
|GENE=
}}
 
'''THROMBIN INHIBITORS WITH RIGID TRIPEPTIDYL ALDEHYDES'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1BB0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=PMS:'>PMS</scene> and <scene name='pdbligand=NVA:'>NVA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Known structural/functional Site: <scene name='pdbsite=CAT:Active+Site'>CAT</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BB0 OCA].  
1BB0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BB0 OCA].  


==Reference==
==Reference==
Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes., Krishnan R, Zhang E, Hakansson K, Arni RK, Tulinsky A, Lim-Wilby MS, Levy OE, Semple JE, Brunck TK, Biochemistry. 1998 Sep 1;37(35):12094-103. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9724521 9724521]
Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes., Krishnan R, Zhang E, Hakansson K, Arni RK, Tulinsky A, Lim-Wilby MS, Levy OE, Semple JE, Brunck TK, Biochemistry. 1998 Sep 1;37(35):12094-103. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9724521 9724521]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: hydrolase]]
[[Category: hydrolase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:53:23 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:08:40 2008''
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