1i9b: Difference between revisions

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Revision as of 17:43, 25 July 2012

File:1i9b.png

Template:STRUCTURE 1i9b

X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP)

Template:ABSTRACT PUBMED 11357122

About this Structure

1i9b is a 5 chain structure of Acetylcholine binding protein with sequence from Lymnaea stagnalis. Full crystallographic information is available from OCA.

See Also

Reference

  1. Brejc K, van Dijk WJ, Klaassen RV, Schuurmans M, van Der Oost J, Smit AB, Sixma TK. Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors. Nature. 2001 May 17;411(6835):269-76. PMID:11357122 doi:10.1038/35077011
  2. Karlin A. Emerging structure of the nicotinic acetylcholine receptors. Nat Rev Neurosci. 2002 Feb;3(2):102-14. PMID:11836518 doi:10.1038/nrn731
  3. Grutter T, Prado de Carvalho L, Le Novere N, Corringer PJ, Edelstein S, Changeux JP. An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors. EMBO J. 2003 May 1;22(9):1990-2003. PMID:12727867 doi:10.1093/emboj/cdg197

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