1blh: Difference between revisions

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[[Image:1blh.gif|left|200px]]<br /><applet load="1blh" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1blh.gif|left|200px]]
caption="1blh, resolution 2.3&Aring;" />
 
'''STRUCTURE OF A PHOSPHONATE-INHIBITED BETA-LACTAMASE. AN ANALOG OF THE TETRAHEDRAL TRANSITION STATE(SLASH)INTERMEDIATE OF BETA-LACTAM HYDROLYSIS'''<br />
{{Structure
|PDB= 1blh |SIZE=350|CAPTION= <scene name='initialview01'>1blh</scene>, resolution 2.3&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=FOS:[[N-(BENZYLOXYCARBONYL)AMINO]METHYL]PHOSPHATE'>FOS</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6]
|GENE=
}}
 
'''STRUCTURE OF A PHOSPHONATE-INHIBITED BETA-LACTAMASE. AN ANALOG OF THE TETRAHEDRAL TRANSITION STATE(SLASH)INTERMEDIATE OF BETA-LACTAM HYDROLYSIS'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1BLH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus] with <scene name='pdbligand=FOS:'>FOS</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BLH OCA].  
1BLH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BLH OCA].  


==Reference==
==Reference==
Structure of a phosphonate-inhibited beta-lactamase. An analog of the tetrahedral transition state/intermediate of beta-lactam hydrolysis., Chen CC, Rahil J, Pratt RF, Herzberg O, J Mol Biol. 1993 Nov 5;234(1):165-78. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8230196 8230196]
Structure of a phosphonate-inhibited beta-lactamase. An analog of the tetrahedral transition state/intermediate of beta-lactam hydrolysis., Chen CC, Rahil J, Pratt RF, Herzberg O, J Mol Biol. 1993 Nov 5;234(1):165-78. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8230196 8230196]
[[Category: Beta-lactamase]]
[[Category: Beta-lactamase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: hydrolase(beta-lactamase)]]
[[Category: hydrolase(beta-lactamase)]]


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