1bp4: Difference between revisions
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[[Image:1bp4.gif|left|200px]] | [[Image:1bp4.gif|left|200px]] | ||
'''USE OF PAPAIN AS A MODEL FOR THE STRUCTURE-BASED DESIGN OF CATHEPSIN K INHIBITORS. CRYSTAL STRUCTURES OF TWO PAPAIN INHIBITOR COMPLEXES DEMONSTRATE BINDING TO S'-SUBSITES.''' | {{Structure | ||
|PDB= 1bp4 |SIZE=350|CAPTION= <scene name='initialview01'>1bp4</scene>, resolution 2.2Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=ALD:CARBOBENZYLOXYLEUCINYL-LEUCINYL-LEUCINAL'>ALD</scene> | |||
|ACTIVITY= | |||
|GENE= | |||
}} | |||
'''USE OF PAPAIN AS A MODEL FOR THE STRUCTURE-BASED DESIGN OF CATHEPSIN K INHIBITORS. CRYSTAL STRUCTURES OF TWO PAPAIN INHIBITOR COMPLEXES DEMONSTRATE BINDING TO S'-SUBSITES.''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1BP4 is a [ | 1BP4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Carica_papaya Carica papaya]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BP4 OCA]. | ||
==Reference== | ==Reference== | ||
Use of papain as a model for the structure-based design of cathepsin K inhibitors: crystal structures of two papain-inhibitor complexes demonstrate binding to S'-subsites., LaLonde JM, Zhao B, Smith WW, Janson CA, DesJarlais RL, Tomaszek TA, Carr TJ, Thompson SK, Oh HJ, Yamashita DS, Veber DF, Abdel-Meguid SS, J Med Chem. 1998 Nov 5;41(23):4567-76. PMID:[http:// | Use of papain as a model for the structure-based design of cathepsin K inhibitors: crystal structures of two papain-inhibitor complexes demonstrate binding to S'-subsites., LaLonde JM, Zhao B, Smith WW, Janson CA, DesJarlais RL, Tomaszek TA, Carr TJ, Thompson SK, Oh HJ, Yamashita DS, Veber DF, Abdel-Meguid SS, J Med Chem. 1998 Nov 5;41(23):4567-76. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9804696 9804696] | ||
[[Category: Carica papaya]] | [[Category: Carica papaya]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: sulfhydryl proteinase]] | [[Category: sulfhydryl proteinase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:13:59 2008'' | ||
