2h2q: Difference between revisions

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==About this Structure==
==About this Structure==
[[2h2q]] is a 2 chain structure of [[Dihydrofolate reductase]] and [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H2Q OCA].  
[[2h2q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H2Q OCA].  


==See Also==
==See Also==

Revision as of 08:39, 20 October 2012

File:2h2q.png

Template:STRUCTURE 2h2q

Crystal structure of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate synthase

Template:ABSTRACT PUBMED 18536013

About this Structure

2h2q is a 2 chain structure with sequence from Trypanosoma cruzi. Full crystallographic information is available from OCA.

See Also

Reference

  1. Schormann N, Senkovich O, Walker K, Wright DL, Anderson AC, Rosowsky A, Ananthan S, Shinkre B, Velu S, Chattopadhyay D. Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function. Proteins. 2008 Dec;73(4):889-901. PMID:18536013 doi:10.1002/prot.22115

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