2wf2: Difference between revisions
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Revision as of 20:58, 25 July 2012
HUMAN BACE-1 IN COMPLEX WITH 8-ETHYL-N-((1S,2R)-2-HYDROXY-3-(((3-(METHYLOXY)PHENYL)METHYL)AMINO)-1-(PHENYLMETHYL) PROPYL)-1-METHYL-3,4,7,8-TETRAHYDRO-1H,6H-(1,2,5) THIADIAZEPINO(5,4,3-DE)QUINOXALINE-10-CARBOXAMIDE 2,2-DIOXIDE
Template:ABSTRACT PUBMED 19477642
About this Structure
2wf2 is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Charrier N, Clarke B, Demont E, Dingwall C, Dunsdon R, Hawkins J, Hubbard J, Hussain I, Maile G, Matico R, Mosley J, Naylor A, O'Brien A, Redshaw S, Rowland P, Soleil V, Smith KJ, Sweitzer S, Theobald P, Vesey D, Walter DS, Wayne G. Second generation of BACE-1 inhibitors part 2: Optimisation of the non-prime side substituent. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3669-73. Epub 2009 Apr 5. PMID:19477642 doi:10.1016/j.bmcl.2009.03.150
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Memapsin 2
- Brien, A O.
- Charrier, N.
- Clarke, B.
- Demont, E.
- Dingwall, C.
- Dunsdon, R.
- Hawkins, J.
- Hubbard, J.
- Hussain, I.
- Maile, G.
- Matico, R.
- Mosley, J.
- Naylor, A.
- Redshaw, S.
- Rowland, P.
- Smith, K J.
- Soleil, V.
- Sweitzer, S.
- Theobald, P.
- Vesey, D.
- Walter, D S.
- Wayne, G.
- Asp-2
- Aspartyl protease
- Bace-1
- Beta-secretase
- Beta-site app cleaving enzyme
- Disulfide bond
- Glycoprotein
- Hydrolase
- Memapsin-2
- Membrane
- Protease
- Transmembrane
- Zymogen
