1qx3: Difference between revisions

Revision as of 21:14, 25 July 2012

Gene:

CASP3 OR CPP32 (Homo sapiens)

Structural annotation:
Resources:	CATH : 1Qx3A00 InterPro : Ipr001309, Ipr015917, Ipr011600, Ipr002138, Ipr015470, Ipr002398 Pfam : PF00656 SCOP : d1qx3a_ UniProt : P42574

Functional annotation:
Cellular component:	cytoplasm
Biological process:	apoptosis proteolysis induction of apoptosis nuclear fragmentation during apoptosis
Molecular function:	caspase activity peptidase activity protein binding hydrolase activity cysteine-type peptidase activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

1qx3 is a 1 chain structure of Caspase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Ni CZ, Li C, Wu JC, Spada AP, Ely KR. Conformational restrictions in the active site of unliganded human caspase-3. J Mol Recognit. 2003 May-Jun;16(3):121-4. PMID:12833566 doi:10.1002/jmr.615

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