1yy9: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[1yy9]] is a 3 chain structure | [[1yy9]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The June 2010 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Epidermal Growth Factor Receptor'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2010_6 10.2210/rcsb_pdb/mom_2010_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YY9 OCA]. | ||
==See Also== | ==See Also== | ||
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[[Category: Epidermal Growth Factor Receptor]] | [[Category: Epidermal Growth Factor Receptor]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: RCSB PDB Molecule of the Month]] | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
Revision as of 09:08, 20 October 2012
Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225
Template:ABSTRACT PUBMED 15837620
About this Structure
1yy9 is a 3 chain structure with sequence from Homo sapiens. The June 2010 RCSB PDB Molecule of the Month feature on Epidermal Growth Factor Receptor by David Goodsell is 10.2210/rcsb_pdb/mom_2010_6. Full crystallographic information is available from OCA.
See Also
Reference
- Li S, Schmitz KR, Jeffrey PD, Wiltzius JJ, Kussie P, Ferguson KM. Structural basis for inhibition of the epidermal growth factor receptor by cetuximab. Cancer Cell. 2005 Apr;7(4):301-11. PMID:15837620 doi:10.1016/j.ccr.2005.03.003
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Epidermal Growth Factor Receptor
- Homo sapiens
- RCSB PDB Molecule of the Month
- Receptor protein-tyrosine kinase
- Ferguson, K M.
- Jeffrey, P D.
- Kussie, P.
- Li, S.
- Schmitz, K R.
- Wiltzius, J J.W.
- Antigen:antibody complex
- Antitumor
- Cell surface receptor
- Drug
- Fab fragment
- Glycoprotein
- Immune system-transferase complex
- Tyrosine kinase