1c25: Difference between revisions

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[[Image:1c25.gif|left|200px]]<br /><applet load="1c25" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1c25.gif|left|200px]]
caption="1c25, resolution 2.3&Aring;" />
 
'''HUMAN CDC25A CATALYTIC DOMAIN'''<br />
{{Structure
|PDB= 1c25 |SIZE=350|CAPTION= <scene name='initialview01'>1c25</scene>, resolution 2.3&Aring;
|SITE= <scene name='pdbsite=DSU:CYS+A+384+And+CYS+A+340+May+Form+Disulfide+Bond+Under+Ce+...'>DSU</scene> and <scene name='pdbsite=POP:Putative+Phosphate+Binding+Loop,+CYS-X(5)-ARG+Signature+...'>POP</scene>
|LIGAND=
|ACTIVITY= [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48]
|GENE= CDC25A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''HUMAN CDC25A CATALYTIC DOMAIN'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1C25 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Active as [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] Known structural/functional Sites: <scene name='pdbsite=DSU:CYS+A+384+And+CYS+A+340+May+Form+Disulfide+Bond+Under+Ce+...'>DSU</scene> and <scene name='pdbsite=POP:Putative+Phosphate+Binding+Loop,+CYS-X(5)-ARG+Signature+...'>POP</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C25 OCA].  
1C25 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C25 OCA].  


==Reference==
==Reference==
Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A., Fauman EB, Cogswell JP, Lovejoy B, Rocque WJ, Holmes W, Montana VG, Piwnica-Worms H, Rink MJ, Saper MA, Cell. 1998 May 15;93(4):617-25. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9604936 9604936]
Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A., Fauman EB, Cogswell JP, Lovejoy B, Rocque WJ, Holmes W, Montana VG, Piwnica-Worms H, Rink MJ, Saper MA, Cell. 1998 May 15;93(4):617-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9604936 9604936]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Protein-tyrosine-phosphatase]]
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[[Category: hydrolase]]
[[Category: hydrolase]]


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